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REVISION NOTE

Substitution and aliphatic compounds

Stuart Thompson looks at nucleophilic substitution reactions of aliphatic compounds

In CHEMISTRY REVIEW, Vol. 30, No. 3, pp. 32–33 we learnt about substitution reactions of aromatic compounds. Here we will look at nucleophilic substitution reactions in aliphatic compounds and see how the arrangement of the groups in the product results from the reaction mechanism.

An aliphatic molecule is an organic compound that has its carbon atoms in a chain, rather than in closed rings (as in aromatic and alicyclic compounds). Examples of aliphatic compounds include non-cyclic alkanes, alkenes, alkynes and their derivatives.

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