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Improving natural medicines

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chemistry online

Picture it… Chemistry

Picture it… Chemistry (www.chempics.wordpress.com) is a visually appealing blog that looks at the science behind substances encountered in familiar objects. CHEMISTRY REVIEW invited Natalie Fey and Jenny Slaughter from the University of Bristol, founders and editors of the project, to select some highlights

Figure 3 The molecule vanillin is exactly the same, regardless of whether it has been synthesised by chemists or produced by the orchid

Many of our blog posts are centred around compounds found in plants. By bringing interesting plants into a laboratory setting and exploring the uses of some of the molecules produced by them, we hope to challenge the divide between nature and laboratory.

Take chillies (Figure 1). Not only can they spice up food, but they also have antimicrobial and antifungal properties. While they have been used in pepper sprays to fend off angry humans, curious bears and hungry elephants, this would not work on birds. Differences in physiology mean that birds cannot experience the heat and pain of a hot chilli (see CHEMISTRY REVIEW, Vol. 22, No. 1, p. 34). The key molecule in chilli is capsaicin, and the 1-hydroxy-2-methoxybenzene part of its structure is also found in vanillin (Figure 2), the topic of another blog post.

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Improving natural medicines

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Nuclear magnetic resonance

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