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bioethics

Genome editing

Promises and problems

It has become relatively easy to add, alter, inactivate and remove genes from genomes. Bioethicist John Bryant explains some of the potential benefits and downsides in relation to human health and agriculture

Methods for cutting DNA out of genomes were first developed in the late 1990s. They were useful because they enabled the very precise ‘knock-out’ of specific genes in order to study gene function. But they were relatively cumbersome and could only be used on one gene at a time. This changed with the arrival of genome-editing methods based on a type of bacterial DNA called CRISPR.

CRISPR

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